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Ronald B. Walter, Ph.D.


Professor and University Chair in Cancer Research

Director, Xiphophorus Genetic Stock Center

Ron Walter

Office: 419 Centennial Hall, Texas State University, San Marcos, TX

Email: RWalter@txstate.edu

Office Phone: (512) 245-0357

Curriculum Vitae

Publications: Book Chapters, Monographs, and Peer Reviewed Manuscripts


Recent Publications (last 5 years)

Manuscripts

Childress, W.M., Bosworth, B., Vhesney, E., Walter, R.B., Tiersch, T.R. (2019). On-site Capabilities if a Mobile Laboratory for Sperm Cryopreservation of Blue Catfish (Ictalurus furcatus), Xiphophorus species, and red Snapper (Lutjanus campechanus), North American Journal of Aquaculture, May 2019, DOI:10.1002/naaq.10099

Klotz, B., Kneitz, S., Regensburger, M., Dannemann, M., Kelso, J., Lu, Y., Boswell W., Postlethwait, J., Warren, W., Kunz, M., Walter, R.B. and M. Schartl (2018). Expression signatures of early-stage and advanced medaka melanomas. Comp. Biochem. Physiol. Part C, 208:20-28 https://doi.org/10.1016/j.cbpc.2017.11.005

Boswell, M., Lu, Y., Boswell, W., Hildreth, K., Salinas, R., Walter, C.A., Walter, R.B (2018). Fluorescent Light Incites a Conserved Immune and Inflammatory Genetic Response within Vertebrate Organs (Danio rerio,Oryzias latipes, and Mus musculus). Genes, 10:271 https://doi.org/10.3390/genes10040271

Lu, Y., Boswell, W., Boswell, M., Klotz, B, Kneitz, S., Regneri, J., Savage, M., Mendoza. C., Postlethwait. J., Warren, W.C., Schartl, M., Walter, RB. (2018). Application of the Transcriptional Disease Signatures (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish Model, Scientific Reports, 9:530-543. doi.org/10.1038/s44158-018-36656-x

Lu, Y., Boswell, M., Boswell, W., Kneitz, S., Klotz, B., Regneri, J., Savage, M., Postlethwait, J., Warren, W., Schartl, M., and R.B. Walter (2018). Gene Expression Variation and Parental Allele Inheritance in Xiphophorus Interspecies Hybridization Model. PLoS Genetics, December 26, 2018, https://doi.org/10.1371/journal.pgen.1007875

Gonzalez, T. J., Lu, Y., Boswell, M., Boswell, W., Medrano, G., Walter, S., Ellis, S., Savage, M., Varga, Z. M., Lawrence, C., Sanders, G., and Walter, R. B. (2018). Fluorescent light exposure incites acute and prolonged immune responses in zebrafish (Danio rerio) skin. Comp. Biochem. Physiol. C Toxicol Pharmacol. 2017 Sep 29. pii: S1532-0456(17)30164-3. doi: 10.1016/j.cbpc.2017.09.009

Boswell, M., Boswell, W., Lu, Y., Savage, M., Mazurek, Z., Chang, J., Muster, J., and Walter, R. (2018). The transcriptional response of skin to fluorescent light exposure in viviparous (Xiphophorus) and oviparous (Danio, Oryzias) fishes. Comp. Biochem. Physiol. Part C Toxicol Pharmacol. 2017 Oct 7. pii: S1532-0456(17)30169-2. doi: 10.1016/j.cbpc.2017.10.003

Boswell, W. T., Boswell, M., Walter, D. J., Navarro, K. L., Chang, J., Lu, Y., Savage, M. G., Shen, J., and Walter, R. B. (2018). Exposure to 4,100K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin. Comp. Biochem. Physiol. Part C Toxicol Pharmacol. 2017 Sep 29. pii: S1532-0456(17)30163-1. doi: 10.1016/j.cbpc.2017.09.008

Klotz, B., Kneitz, S., Regensburger, M., Dannemann, M., Kelso, J., Lu, Y., Boswell W., Postlethwait, J., Warren, W., Kunz, M., Walter, R.B. and M. Schartl (2018). Expression signatures of early-stage and advanced medaka melanomas. Comp. Biochem. Physiology, Part C, 208:20-28 https://doi.org/10.1016/j.cbpc.2017.11.005

Lu, Yuan, Reyes, J., Walter, S., Gonzalez, T., Medrano, G., Boswell, M., Boswell, W., Savage, S. and R.B. Walter (2018). Characterization of Basal Gene Expression Trends Over a Diurnal Cycle in Xiphophorus maculatus Skin, Brain and Liver. Comp. Biochem. & Physiology, Part C, 208:2-11, https://doi.org/10.1016/j.cbpc.2017.11.013

Wise, J.P. Jr., Wise, T.F., Wise, C.F., Wise, S.S., Gianos, C. Jr. , , Xie, H., Walter, R.B., Boswell, M., Zhu, C., Zheng, T., Perins, C., and J.P. Sr.,Wise. (2018).  A three-year study of metal levels in skin biopsies of whales in the Gulf of Mexico after the Deepwater Horizon oil crisis. Comp. Biochem. & Physiology, Part C, 205:15-25, https://doi.org/10.1016/j.cbpc.2017.12.003

Warren, W.C., Kuderna, L., Alexander, A., Catchen, J., Pérez-Silva, J.G., López-Otín, Víctor Quesada, C., Minx, P., Tomlinson, C., Montague, M., Farias, F.H.G., Walter, R.B., Marques-Bonet, T., Glenn, T., Kieran, T.J., Wise, S.S., Wise Jr., J.P., Waterhouse, R.M., and J.P. Wise, Sr. (2018). The novel evolution of the sperm whale genome.  Genome Biol. Evololution 9(12):3260-3264. https://doi.org/10.1093/gbe/evx187

Lu, Y., Boswell, M., Boswell, W., Kneitz, S., Hausmann, M., Klotz, B., Regneri, J., Savage, M., Amores, A., Postlethwait, J., Warren, W., Schartl, M., and R. B. Walter (2018). Comparison of Xiphophorus and Human Melanoma Transcriptomes Reveals Conserved Pathway Interactions, Pigment Cell Melanoma Res., 2018:1-13, https://doi.org/10.1111/pcmr.12686  (Cover photo selection)

Warren, W., García-Pérez, R., Xu, S., Lampert, K., Chalopin, D., Stöck, M., Loewe, L., Lu, Y., Kuderna, L., Minx, P., Montague, M., Tomlinson, C., Hillier, L., Murphy, D., Wang, J., Wang, Z., Garcia, C.M., Thomas, G., Volff, J-N., Farias, F., Aken, B., Walter, R.B., Pruitt, K., Marques-Bonet, T., Hahn, M., Kneitz, S., Lynch, M., and M. Schartl (2018).  Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly, Nature - Evolution and Ecology, 2:669–679, https://doi.org/ 10.1038/s41559-018-0473-y

Walter, R.B., Boswell, M, Chang, J., Boswell, W.T., Lu, Y., Navarro, K, Walter, S.M., Walter, D.J., Salinas, R. and M. Savage (2018).  Waveband Specific Transcriptional Control of Select Genetic Pathways in Vertebrate Skin. BMC Genomics, 19:355-373.  https://doi.org/10.1186/s12864-018-4735-5

Regneri, J., Klotz, B., Wilde, B., Kottler, V., Hausmann, M., Kneitz, S., Regensburger, M., Maurus, K., Götz, R., Lu, Y., Walter, R., Herpin, A., and M. Schartl (2018). Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka, Pigment Cell Melanoma Res. 2018;00:1–11, https://doi.org/10.1111/pcmr.12729  (Cover photo selection)

Zavadil, J., Herzig, M., Hildreth, K., Foroushani, A., Boswell, W., Walter, R.B., Reddick, R., White, H., Zare, H., and C. Walter (2018). C3HeB/FeJ Mice Mimic Gene Expression and Pathobiological Features of Human Hepatocellular Carcinoma, Molecular Carcinogenesis. 2018;1–12, https://doi.org/10.1002/mc.22929

Franchini, P., Jones, J., Xiong, P., Kneitz, S., Gompert, Z., Warren, W.C., Walter, R.B., Meyer, A., Schartl. M. (2018).  Long-term experimental hybridisation results in a heterologous transition and the evolution of a new sex chromosome in swordtail fish, Nature Communication. 9:5136, https://doi.org/10.1038/s41467-018-07648-2

Lu, Y., Boswell, M., Boswell, W., Kneitz, S., Hausmann, M., Klotz, B., Regneri, J., Savage, M., Amores, A., Postlethwait, J., Warren, W., Schartl, M., and Walter, R. (2017). Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybrids. Mol Carcinog. 2017 Aug;56(8):1935-1944. doi: 10.1002/mc.22651. Epub 2017 Apr 13.

Lu, Y., Klimovich, C. M., Robeson, K. Z., Boswell, W., Rios-Cardenas, O., Walter, R. B., and Morris, M. R. (2017). Transcriptome assembly and candidate genes involved in nutritional programming in the swordtail fish Xiphophorus multilineatus. PeerJ. 2017 May 2;5:e3275. doi: 10.7717/peerj.3275. eCollection 2017.

Shen, Y., Chalopin, D., Garcia, T., Boswell, M., Boswell, W., Shiryayev, S., Agarwala. R., Volff, J-N, Postlethwait, J.H., Schartl, M., Minx, P., Warren, W.C., and R.B. Walter (2016).  X. couchianus and X. hellerii genome models provide genomic variation insight among Xiphophorus species, BMC Genomics. doi: 10.1186/s12864-015-2361-z

Kneitz, S., Mishra, R., Chalopin, D., Postlethwait, J.H., Warren, W., Walter, R.B., Schartl, M. (2016). Germ cell and tumor associated piRNAs in the medaka and Xiphophorus melanoma models, BMC Genomics, 17:357, DOI:10.1186/s12864-016-2697-z

Song, H., Y. Lu, Z. Qu, V. V. Mossine, M. B. Martin, J. Hou, J. Cui, B. A. Peculis, T. P. Mawhinney, J. Cheng, C. M. Greenlief, K. Fritsche, F. J. Schmidt, R.B. Walter, D. B. Lubahn, G. Y. Sun and Z. Gu (2016). "Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells. Scientific Reports 6: 35323. PMCID 5062119

Boswell, W., Boswell, M., Titus, J., Savage, M., Lu, Y., Shen, J., Walter, R.B. (2015) Sex-specific molecular genetic response to UVB exposure in Xiphophorus maculatus skin. Comp. Biochem. Physiol. Part C. Toxicol Pharmacol., 178:76-85. doi: 10.1016/j.cbpc.2015.07.007. PMID: 26256120

Lu, Y., Boswell, M., Boswell, W., Yang, K., Schartl, M., Walter, R.B. (2015) Molecular genetic response of Xiphophorus maculatus-X. couchianus interspecies hybrid skin to UVB exposure. Comp. Biochem. Physiol. Part C Toxicol Pharmacol., 178:86-92. doi: 10.1016/j.cbpc.2015.07.011 PMID: 26254713

Walter, R.B., Walter, D.J., Boswell, W.T., Caballero, K.L., Boswell, M., Lu, Y., Chang, J., Savage, M.G. (2015) Exposure to fluorescent light triggers down regulation of genes involved with mitotic progression in Xiphophorus skin. Comp. Biochem. Physiol. Part C Toxicol Pharmacol., 178:93-103. doi: 10.1016/j.cbpc.2015.08.006

Chang, J., Lu, Y., Boswell, W.T., Boswell, M., Caballero, K.L., Walter, R.B. (2015) Molecular genetic response to varied wavelengths of light in Xiphophorus maculatus skin. Comp. Biochem. Physiol. Part C. Toxicol. Pharmacol., 178:104-15. doi: 10.1016/j.cbpc.2015.10.002. PMID: 26460196

Schartl, M., Shen, Y., Maurus, K., Walter, R., Tomlinson, C., Wilson, R.K., Postlethwait, J., Warren, W.C. (2015). Whole Body Melanoma Transcriptome Response in Medaka. Plos One doi:10.1371/journal.pone.0143057

Yang, K., Boswell, M., Walter, D.J., Downs, K., Gaston-Pravia, Garcia, T., Shen, Y. Mitchell, D.L. and R.B. Walter (2014). UVB-induced Gene Expression in the Skin of Xiphophorus maculatus Jp163 B. Comp. Biochem. Physiol. Part C, 163:86-94.  doi: 10.1016/j.cbpc.2014.01.008, PMID 24496042

Walter, D.J., Boswell, M., Volk de García, S., Walter, S.M., Breitenfeldt, E.W., Boswell W., and R. B. Walter (2014).  Characterization and Differential Expression of DNA Photolyases in Xiphophorus. Comp. Bioch. Physiol. Part C, 163: 77-85. doi: 10.1016/j.cbpc.2014.01.006, PMID 24496042

Contreras, A.J., Boswell, M., Downs, K.P., Pasquali, A., Mitchell, D.L. and R.B. Walter (2014) Cortisol Release in Response to UVB Exposure in Xiphophorus Fish. Comp. Bioch. Physiol. Part C, 163:95-101. doi: 10.1016/j.cbpc.2014.02.004, PMID 24625568

Amores, A., Catchen, C., Nanda, I., Warren, W., Walter, R.B., and M. Schartl and J.H. Postlethwait (2014).  A Rad-tag genetic map for the playtfish (Xiphophorus maculatus) reveals mechanisms of karyotype evolution among teleost fish. Genetics, 197 2):625-641. doi: 10.1534/genetics.114.164293, PMID 24700104

Garcia T.I., Matos I., Shen, Y., Pabuwal V., Coelho, M.M., Wakamatsu, Y., Schartl, M., and R.B. Walter (2014). Novel Method for Analysis of Allele Specific Expression in Triploid Oryzias latipes Reveals Consistent Pattern of Allele Exclusion. PLOS ONE, 9(6): e100250. doi: 10.1371/journal.pone.0100250, PMID 24945156

Walter, D.J., Boswell, M., Volk de García, S., Walter, S.M., Breitenfeldt, E.W., Boswell W., and R. B. Walter (2014).  Characterization and Differential Expression of DNA Photolyases in Xiphophorus. Comp. Bioch. Physiol. Part C, 163: 77-85. doi: 10.1016/j.cbpc.2014.01.006, PMID 24496042

Book Chapters & Monographs

Xiphophorus Genetic Stock Center. Genetic Resources of Model Organisms – Strategies for Conservation”, R. Jarret (ed.), CRC Press Boca Raton, FL, Taylor and Francis Publishing, Chapter 13, 25 pgs

Hagedorn, M., Varga, Z., Walter, R.B, TierschT.R. (2018).  Workshop Report: Cryopreservation of Aquatic Biomedical Models, Cryobiology, 2018:110.264. https://doi.org/10.1016/j.cryobiol.2018.10.264

Schartl, M., and R.B. Walter (2016). Xiphophorus and Medaka Cancer ModelsAdvances in Experimental Medicine and Biology: Cancer and Zebrafish Mechanisms, Techniques and Models, D. Langenau (ed.), Springer Publishing, pp527-548, Switzerland, https://doi.org/10.1007/978-3-319-30654-4_23

Lu, Y., Shen, Y., Warren, W., and R. B. Walter (2015). “Next Generation Sequencing in Aquatic Models”.  In: "Next Generation Sequencing – Advances, Applications, and Challenges", ISBN 978-953-51-4594-3. Jerrzy K. Kuliski, editor, INTECH Publications. Janeza Trdine 9, 51000, Rijeka, Croatia. http://dx.doi.org/10.5772/61657

Walter, R.B., and T. Obara (2015).  Workshop Report: The Medaka Model for Comparative Assessment of Human Disease Mechanisms, Aquatic Animal Models of Human Disease: Selected Papers and Recommendations form the 7th Conference. Comparative Biochemistry and Physiology, Part C, 178: 156-162